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Page 1
Human 2'-Deoxynucleoside 5'-Phosphate N-Hydrolase 1: Mechanism of 2'-Deoxyuridine 5'-Monophosphate Hydrolysis.
Biochemistry. 2023 Sep 5;62(17):2658-2668. doi: 10.1021/acs.biochem.3c00369. Epub 2023 Aug 15.
Biochemistry. 2023.
PMID: 37582341
Free PMC article.
Catalytic Cycle of the Bifunctional Enzyme Phosphoribosyl-ATP Pyrophosphohydrolase/Phosphoribosyl-AMP Cyclohydrolase.
Fisher G, Pečaver E, Read BJ, Leese SK, Laing E, Dickson AL, Czekster CM, da Silva RG.
Fisher G, et al. Among authors: dickson al.
ACS Catal. 2023 May 23;13(11):7669-7679. doi: 10.1021/acscatal.3c01111. eCollection 2023 Jun 2.
ACS Catal. 2023.
PMID: 37288093
Free PMC article.
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Identification of unusual oxysterols biosynthesised in human pregnancy by charge-tagging and liquid chromatography - mass spectrometry.
Dickson AL, Yutuc E, Thornton CA, Wang Y, Griffiths WJ.
Dickson AL, et al.
Front Endocrinol (Lausanne). 2022 Nov 10;13:1031013. doi: 10.3389/fendo.2022.1031013. eCollection 2022.
Front Endocrinol (Lausanne). 2022.
PMID: 36440193
Free PMC article.
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Snapshots of the Reaction Coordinate of a Thermophilic 2'-Deoxyribonucleoside/ribonucleoside Transferase.
Tang P, Harding CJ, Dickson AL, da Silva RG, Harrison DJ, Czekster CM.
Tang P, et al. Among authors: dickson al.
ACS Catal. 2024 Feb 13;14(5):3090-3102. doi: 10.1021/acscatal.3c06260. eCollection 2024 Mar 1.
ACS Catal. 2024.
PMID: 38449528
Free PMC article.
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The novel anti-cancer fluoropyrimidine NUC-3373 is a potent inhibitor of thymidylate synthase and an effective DNA-damaging agent.
Bré J, Dickson AL, Read OJ, Zhang Y, McKissock FG, Mullen P, Tang P, Zickuhr GM, Czekster CM, Harrison DJ.
Bré J, et al. Among authors: dickson al.
Cancer Chemother Pharmacol. 2023 May;91(5):401-412. doi: 10.1007/s00280-023-04528-5. Epub 2023 Mar 31.
Cancer Chemother Pharmacol. 2023.
PMID: 37000221
Free PMC article.
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Bile acid biosynthesis in Smith-Lemli-Opitz syndrome bypassing cholesterol: Potential importance of pathway intermediates.
Abdel-Khalik J, Hearn T, Dickson AL, Crick PJ, Yutuc E, Austin-Muttitt K, Bigger BW, Morris AA, Shackleton CH, Clayton PT, Iida T, Sircar R, Rohatgi R, Marschall HU, Sjövall J, Björkhem I, Mullins JGL, Griffiths WJ, Wang Y.
Abdel-Khalik J, et al. Among authors: dickson al.
J Steroid Biochem Mol Biol. 2021 Feb;206:105794. doi: 10.1016/j.jsbmb.2020.105794. Epub 2020 Nov 24.
J Steroid Biochem Mol Biol. 2021.
PMID: 33246156
Free PMC article.
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Deep mining of oxysterols and cholestenoic acids in human plasma and cerebrospinal fluid: Quantification using isotope dilution mass spectrometry.
Yutuc E, Dickson AL, Pacciarini M, Griffiths L, Baker PRS, Connell L, Öhman A, Forsgren L, Trupp M, Vilarinho S, Khalil Y, Clayton PT, Sari S, Dalgic B, Höflinger P, Schöls L, Griffiths WJ, Wang Y.
Yutuc E, et al. Among authors: dickson al.
Anal Chim Acta. 2021 Apr 15;1154:338259. doi: 10.1016/j.aca.2021.338259. Epub 2021 Feb 4.
Anal Chim Acta. 2021.
PMID: 33736801
Free PMC article.
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